PUBLICATIONS

[International journal]

•K. Yoshimoto, K. Maki, T. Adachi, K. Kamei, Cyclic Stretching Enhances Angiocrine Signals at Liver Bud Stage from hPSCs in 2-Dimensional Culture. Tissue Engineering Part A. (2023)

• S. Imamura, K. Yoshimoto, S. Terada, K. Takamuro, K. Kamei, In vitro culture at 39 °C during hepatic maturation of human ES cells facilitates hepatocyte-like cell functions. Sci. Rep. 12, 5155 (2022).

• X. Wen, K. Yoshimoto, M. Yamanaka, S. Terada, K. Kamei, In vitro nonalcoholic fatty liver disease model with cyclo-olefin-polymer-based microphysiological systems. Organs-on-a-Chip 3, 100010 (2021).

• K. Yoshimoto, N. Minier, J. Yang, S. Imamura, K. Stocking, J. Patel, S. Terada, Y. Hirai, K. Kamei, Recapitulation of Human Embryonic Heartbeat to Promote Differentiation of Hepatic Endoderm to Hepatoblasts. Front. Bioeng. Biotechnol. 8, 1–11 (2020).

• Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array, Y. Mashimo, M. Yoshioka, Y. Tokunaga, C. Fockenberg, S. Terada, Y. Koyama, T. Shibata-Seki, K. Yoshimoto, R. Sakai, H. Hakariya, L. Liu, T. Akaike, E. Kobatake, S.E. How, M. Uesugi, Y. Chen, K. Kamei*, Journal of Visualized Experiments (JoVE), 139, e57377 (2018); DOI:10.3791/57377

[Japanese journal]

• 生体機能の再現を目指したbody-on-a-chip, K. Yoshimoto, K. Kamei, Farumashia, 55(5), 427-431 (2019); DOI: 10.14894/faruawpsj.55.5_427

HONORS AND AWARDS

• Research Fellowship for Young Scientists, DC1, by Japan Society for the Promotion of Science - ¥7,200,000/3 years (2022-2025)

• Tuition exemption in Kyoto University (2022-2025)

• Nakatani Foundation for advancement of measuring technology in biomedical engineering - ¥7,800,000/3.5 years (2021-2025)

• Japan Student Service Organization, scholarship - ¥2,112,000/2 years (2020-2022)

• 27th the Japanese Society for the Research of Hepatic cells, Presentation outstanding award (2020)

• The International Genetically Engineered Machine competition, Boston, silver medal, as team leader (2017)

• The International Genetically Engineered Machine competition, Boston, gold medal (2016)

GRANTS

• Japan Society for the Promotion of Science, Grant-in-Aid for JSPS Fellows - ¥3,400,000/3 years (2022-24)

• The Sasakawa Scientific Research Grant from The Japan Science Society - ¥700,000/year (2021)

• Student Projects for Enhancing Creativity in Kyoto university - ¥500,000/year (2017)

CONFERENCE PRESENTATIONS

[International conference]

ORAL PRESENTATION

• K. Yoshimoto, K. Maki, T. Adachi, K. Kamei. (2023, August). 

“CYCLIC STRETCH PROMOTES HGF AND MMP9 SECRETIONS FROM HEPATOBLASTS AND ENDOTHELIAL CELLS”

 6th Japan-Switzerland Workshop on Biomechanics, Otaru, Japan.  -->program

• K. Yoshimoto, K. Maki, T. Adachi, K. Kamei. (2022, July). 

“Cyclic mechanical strain of foregut endoderm cells promotes hepatic differentiation”

9th World Congress of Biomechanics, Taipei, Taiwan.

Cell Biomechanics 2: Mechanobiology O-03134   --> program

POSTER PRESENTATION

• K. Yoshimoto, J. Yang, Y. Hirai, K. Maki, T. Adachi, K. Kamei. (2021, July). 

“A microfluidic platform for mechanical stretching stimulation to promote hepatic differentiation from human pluripotent stem cells”

MBI 3M, Online.

• K. Yoshimoto, S. Imamura, S. Terada, K. Kamei. (2021, June). 

“OSCILLATED MECHANICAL STIMULATION FACILITATES FUNCTIONAL DIFFERENTIATION OF HEPATOBLASTS”, International Society for Stem Cell Research 2021 Annual Meeting, Online.

-->program

[Japanese conference]

・第22回　日本再生医療学会総会 2023.3.23-25

周期的力学刺激が促進する上皮 - 間葉転換による肝芽形成

吉本 昂希 O-34-3  -->program

・CHEMINAS44 化学とマイクロ・ナノシステム学会　第44回研究会　11月9-11日

シクロオレフィンポリマー製マイクロ流体デバイスを用いた非アルコール性脂肪肝モデル

吉本昂希  3P-10  -->program

・The 27th Annual Meeting of the Japanese Society for the Research of Hepatic Cells

内胚葉細胞から肝芽細胞への分化における伸展力学刺激の影響解析

吉本昂希、今村聡、寺田志穂、亀井謙一郎 --> program

・CHEMINAS 40th (2019年11月19 - 21日) (oral, poster)

マイクロ流体デバイスを用いた物理刺激による多能性幹細胞から肝細胞様細胞への分化促進

吉本昂希 1,2、今村聡 1、寺田志穂 1、亀井謙一郎 1

1. 京都大学高等研究院物質−細胞統合システム拠点, 2. 京都大学薬学部

---> program

[OHERS]

・16th International Student Seminar (28th-29th Feb. 2018) (oral, poster)

The attempt to kill pine-wood nematodes by feeding RNAi

Yu Do, Koki Yoshimoto, Akiko Fukuda, Ayaka Soda, Ikumi Tsuzuki)

---> progaram

・2017 the international genetically engineering machine competition (Oral, Poster)

silver medal

---> wiki

・2016 the international genetically engineering machine competition (Poster)

gold medal

---> wiki

• 化学とマイクロ・ナノシステム学会 CHEMINAS 40th (2019年11月19 - 21日)

熱刺激によるヒト多能幹細胞由来肝実質細胞の CYP 活性増強効果

今村聡 1, 吉本昂希 1,2, 寺田志穂 1, 亀井謙一郎 1

1. 京都大学高等研究院物質-細胞統合システム拠点(iCeMS) ,

2. 京都大学薬学部薬科学科

• 2019年度シンポジウム「細胞アッセイ技術の現状と将来」（2020年1月20日）

熱刺激によるhPS細胞由来肝実質細胞のCYP3A4活性増強効果

(京都大学高等研究院物質-細胞統合システム拠点) 今村　聡

(京都大学薬学部薬科学科/ 京都大学高等研究院物質-細胞統合システム拠点) 吉本　昂希

(京都大学高等研究院物質-細胞統合システム拠点) 寺田　志穂, 亀井　謙一郎

MEDIA

・2018　Kyoto university　information booklet　---click---

・2017　Asahi- news paper　Kyoto university ---click---

・2017　Kyoto university funding　---click---